The informed consent process for genetic testing does not commonly address preferences regarding disclosure of results in the event of the patient's death. Adults being tested for familial colorectal cancer were asked whether they want their exome sequencing results disclosed to another person in the event of their death prior to receiving the results. Of 78 participants, 92% designated an individual and 8% declined to. Further research will help refine practices for informed consent.

Background: The factors influencing parents’ willingness to enroll their children in biobanks are poorly understood. This study sought to assess parents’ willingness to enroll their children, and their perceived benefits, concerns, and information needs under different consent and data-sharing scenarios, and to identify factors associated with willingness. Methods: This large, experimental survey of patients at the 11 eMERGE Network sites used a disproportionate stratified sampling scheme to enrich the sample with historically underrepresented groups. Participants were randomized to receive one of (...) three consent and data-sharing scenarios. Results: In total, 90,000 surveys were mailed and 13,000 individuals responded (15.8% response rate). 5737 respondents were parents of minor children. Overall, 55% (95% confidence interval 50–59%) of parents were willing to enroll their youngest minor child in a hypothetical biobank; willingness did not differ between consent and data-sharing scenarios. Lower educational attainment, higher religiosity, lower trust, worries about privacy, and attitudes about benefits, concerns, and information needs were independently associated with less willingness to allow their child to participate. Of parents who were willing to participate themselves, 25% were not willing to allow their child to participate. Being willing to participate but not willing to allow one’s child to participate was independently associated with multiple factors, including race, lower educational attainment, lower annual household income, public health care insurance, and higher religiosity. Conclusions: Fifty-five percent of parents were willing to allow their youngest minor child to participate in a hypothetical biobank. Building trust, protecting privacy, and addressing attitudes may increase enrollment and diversity in pediatric biobanks. (shrink)

This paper re-examines the debate between those who, with Miranda Fricker, diagnose the primary, non-contingent harm of testimonial injustice as a kind of epistemic objectification and those who contend it is better thought of as a kind of epistemic othering. Defenders of the othering account of the primary harm have often argued for it by presenting cases of testimonial injustice in which the testifier’s epistemic agency is affirmed rather than denied, even while their credibility is unjustly impugned. In previous work, (...) I have instead argued that such cases suggest that we need to enrich our conception of epistemic objectification in ways encouraged by Martha Nussbaum’s cluster analysis of objectification. Here I continue to make the case for this approach, and I consider the othering account in more detail. I focus in particular on Gaile Pohlhaus Jr.’s arguments for a version of the othering account in terms of the notion of derivatization, which turns on the idea that only such an account can enable us to properly understand the harms of testimonial injustice, in particular the ways in which it interferes with a subject’s epistemic agency and autonomy, and I’ll argue that such arguments should not sway us. Finally, I’ll further support my contention that it is illuminating and helpful to think of the primary harm of testimonial injustice in terms of epistemic objectification, though I will concede that the notion of epistemic othering may offer further helpful resources for understanding how subjects can be harmed by testimonial injustice. (shrink)

Meno's Paradox from Socrates to Sextus Gail Fine. sense that they consider the issues it raises; and they argue, against its conclusion, that inquiry is possible. Like Plato and Aristotle, they also explain what makes inquiry possible; and they do ...

If social, political, and material transformation is to have a lasting impact on individuals and society, it must be integrated within ordinary experience. Refiguring the Ordinary examines the ways in which individuals' bodies, habits, environments, and abilities function as horizons that underpin their understandings of the ordinary. These features of experience, according to Gail Weiss, are never neutral, but are always affected by gender, race, social class, ethnicity, nationality, and perceptions of bodily normality. While no two people will experience (...) the ordinary in exactly the same way, the multiplicities, possibilities, overlaps, and limitations of day-to-day horizons are always intersubjectively constituted. Weiss turns her attention to changing the conditions and experiences of oppression from ordinary to extraordinary. This book is an impressive phenomenological, feminist reading of the complexities of human experience.M. V. Marder, University of Toronto, Feb. 2009. (shrink)

Neste artigo, pretende-se elucidar a possibilidade do projeto de autonomia como criação e ruptura ontológica. Para tanto, discutimos o Ser como Caos, Abismo, Sem-Fundo e a significação do Ser em relação com as instituições da sociedade em suas formas heterônoma e autônoma.

Concepts are the constituents of thoughts. Therefore, concepts are vital to any theory of cognition. However, despite their widely accepted importance, there is little consensus about the nature and origin of concepts. Thanks to the work of Lawrence Barsalou, Jesse Prinz and others concept empiricism has been gaining momentum within the philosophy and psychology literature. Concept empiricism maintains that all concepts are copies, or combinations of copies, of perceptual representations—that is, all concepts are couched in the codes of perceptual representation (...) systems. It is widely agreed that any satisfactory theory of concepts must account for how concepts semantically compose (the compositionality requirement) and explain how their intentional content is determined (the content determination requirement). In this paper, I argue that concept empiricism has serious problems satisfying these two requirements. Therefore, although stored perceptual representations may facilitate some traditionally conceptual tasks, concepts should not be identified with copies of perceptual representations. (shrink)

Shepherd propounds a theory of mind with a fair claim to be better than Hume’s at explaining the sources of commonly held human beliefs about causal necessity due largely to her relational theory of sense perception. In comparison with Hume’s account, it incorporates a more sophisticated treatment of mental representation, especially the role of relational structure and logical form. Most important, perhaps, Shepherd’s theory enforces the division, obscured by Hume, between the evidence of necessity and the metaphysical foundation of necessity.

Between Preservation and Recreation: Tamil Traditions of Commentary. Edited by Eva Wilden. École Française d’Extrême-Orient Collection Indologie, vol. 109. Pondichéry: Institut Français de Pondichéry / École Française d’Extrême-Orient, 2009. Pp. xiv + 319.

In this article, I analyze survey data from more than 1,000 financial services employees to understand how gender inequality manifests itself in employees' informal networks. I found that even when Black and white women had jobs in which they controlled organizational resources and had ties to powerful employees, they received less work-related help from their network members than did white men. Drawing on status characteristics theory, I explain that network members were less likely to invest in women than in white (...) men because of cultural beliefs that rank women below that of white men. While past research has documented how employers use gender to rank workers and distribute rewards unequally, my research indicates that workers use gender to categorize and rank their network members as well. (shrink)

The social and political turbulence of the present requires a different framework to interpret artistic developments than was used a century ago. This book surveys the resurgence of sociopolitical aesthetics, tracing key currents of theory and practice, and mapping them against the dominant motif of the last decade: crisis. Drawing upon key artists and theorists within this field - including Gregory Sholette, John Roberts, Dave Beech, Gail Day, Martha Rosler, Kirstin Stakemieir and Marina Vishmidt - this book locates (...) the configurations of sociopolitical aesthetics that might energize struggles that are emerging within a radically altered political terrain. (shrink)

Little is known about health care professionals’ perceptions regarding what it means to treat patients and families with respect and dignity in the intensive care unit (ICU) setting. To address this gap, we conducted nine focus groups with different types of health care professionals (attending physicians, residents/fellows, nurses, social workers, pastoral care, etc.) working in either a medical or surgical ICU within the same academic health system. We identified three major thematic domains, namely, intrapersonal (attitudes and beliefs), interpersonal (behaviors), and (...) system (contextual) factors that influence treatment with respect and dignity. Participants suggested strategies for improving treatment of patients and families in the ICU with respect and dignity, as well as the related need for enhancing respect among the multidisciplinary team of clinicians. Implementing these strategies will require innovative educational interventions and leadership. Future research should focus on the design and evaluation of such interventions on the quality of care. (shrink)

This volume in the Oxford Readings in Philosophy looks at central areas in Plato's philosophy: ethics, politics, religion, and the soul. It includes essays on virtue, knowledge, and happiness; justice and happiness; pleasure; Platonic love; feminism; the ideally just state, democracy and totalitarianism; and the nature of the soul and moral motivation.

Este trabajo tiene como propósito exponer los prejuicios de género que hasta el día de hoy prevalece y se reproducen en las instituciones educativas de todos los niveles en nuestro país. La intención es promover la reflexión entre los lectores sobre la forma en que se han emprendido acciones de educación científica hacia las niñas en nuestro país y el escaso interés que se ha prestado al papel que cumplen los estereotipos de género en este proceso.

Instruction in the arts of life is something other than conveying information about them. It is a matter of communication and participation in values of life by means of imagination, and works of art are the most intimate and energetic means of aiding individuals to share in the arts of living. In teaching for aesthetic experience, I ask my students, most of whom are classroom teachers, to bring their lived experiences to each encounter with a work of art to determine (...) the meaning and value for their lives. Central to this engagement is the development of the skills of aesthetic perception and response through the analysis of form and content in dance, drama, music, and the visual arts.2 To provide a.. (shrink)

Ensayo publicado bajo el título "Love and Vision: Iris Murdoch on Eros and the Individual" en: M. Antonaccio y W. Schweiker, Iris Murdoch and the Search for Human Goodness, Chicago, The University of Chicago Press, 1996, pp. 29-53. El objetivo del este ensayo es analizar el lugar que ocupa el amor er.tico en la obra de Iris Murdoch y, en especial, su relaci.n con el descubrimiento moral. Para ello se contraponen dos modelos: el expuesto por Plat.n en el diálogo Fedro (...) y el que opera en la Divina Comedia de Dante. Este an.lisis comparativo servir. de criterio para el examen de los argumentos de la propia Murdoch sobre el amor y permitir. iluminar la procedencia y los matices de la idea de amor erótico que se ponen en funcionamiento en dos de sus más célebres novelas, La máquina del amor sagrado y profano y El príncipe negro. (shrink)

Russell’s enthusiasm for the romantic poet Shelley contradicts the common notion that the philosophical outlook dulls our emotions. Russell loved Shelley even though he was careful to examine the shortcomings of the young poet and of the romantic genre. Furthermore, Russell acknowledged his own weaknesses inherent to his interest in the romantics. Love through a philosophical lens is arguably superior to love through a romantic filter because the former allows for a clear perception of the object. Russell’s passion for Shelley (...) is a case in point. (shrink)

Der lebende Organismus stellt einen bestimmten, individuellen Teil des Universums dar, indem er seine Selbständigkeit abgetrennt von dem übrigen Universum erhält, durch den Teilungseffekt, welcher durch die Anordnung seiner Teile bestimmt wird. Es ist anerkannt, dass die Teilung nicht vollständig ist, jedoch eine beschränkte gegenseitige Beziehung zulässt. Es ist auch anerkannt, dass der Grad der Organisation in einer verwandten Reihe sich ändert von den tiefen Verwickelungen der einfachen Zelle zu den mannigfachen Abwandlungen wie sie beim Menschen auftreten. Die Auffassung von (...) effektiver Teilung ist ausserdem auch fest und substantiell auf der Tatsache begründet, die durch das Vorhandensein der Plasmamembran und Grenzflächen kolloidaler Aggregaten gegeben ist. Betont ist die dynamische Natur der charakteristischen Gleichgewichtszustände und es wird aufmerksam gemacht auf die kontinuierliche Bildung von effektiven Teilungen bei verschiedenen Gleichgewichtszuständen. Weitere Untersuchung der Bedeutung dieser Teilungen ergibt viele interessante Folgerungen. Schwierigkeiten finden sich, wenn man eine derartige Beschreibung auf geistige Phänomena ausdehnt. Zwar bestehen grundlegende Übereinstimmungen, aber es ist schwer sie genau zu definieren. Es ist klar, dass eine Synthese dieser Art notwendigerweise unvollständig ist, aber es schien wertvoll den Versuch zu machen, L'organisme vivant est présenté ici comme une partie définie et individualisée de l'univers maintenant son individualité propre au moyen de „l'effet de partition” déterminé par l'arrangement de ses parties. Il est entendu que la partition n'est pas complète mais permet encore des relations réciproques mais limitées. Il est reconnu aussi que le degré d'organisation varie dans le cours d'une série, des complexités profondes de la cellule aux innombrables modifications exhibées par l'organisme humain. Le concept de la partition effective est basé solidement sur l'évidence présentée par la membrane plasmatique et les limites de phases dans les aggrégations colloidales. De plus il est important de noter spécialement la nature dynamique des équilibres caractéristiques et l'on ne saurait manquer d'attirer l'attention sur la formation continue de partitions effectives aux différents niveaux d'équilibre. L'étude ultérieure de la signification de ces partitions présente un grand nombre d'implications intéressantes. Il est à noter que des difficultés sont rencontrées quand on essaie d'inclure en une description de ce genre les phénomènes mentaux et psychiques. Des stabilités fondamentales existent, mais elles sont difficiles à définir avec précision. Il est évident du reste au lecteur qu'une synthèse telle que celle-ci est nécessairement incomplète mais néanmoins intéressante à faire. (shrink)

The Archaeology of Bhakti II: Royal Bhakti, Local Bhakti. Edited by Emmanuel Francis and Charlotte Schmid. Collection Indologie, no. 132. Pondicherry: Institut Français de Pondichéry; Paris: École Française d’Extrême-Orient, 2016. Pp. x + 609, illus.

This article reviews the recent crisis in Detroit focusing on the placement of an Emergency Manager in charge of financial decisions, and a bankruptcy process. This political disenfranchisement harmed the pensions of city employees and offered valuable real estate to investors at low prices. While the crisis was long in the making, with deindustrialization and residential segregation beginning in the 1950s, the crisis was exacerbated in 2008 with the mortgage crisis and with water shut-offs to residences. The greatest harms were (...) felt by African American families in the city. The article takes toll of the harms suffered and chronicles movements of resistance against Emergency Management and community organizing efforts. (shrink)

This paper analyzes three multiscale modeling techniques that are commonly used in biology and physics and uses those cases to construct a normative framework for tailoring multiscale modeling techniques to specific modeling contexts. I argue that the selection of a multiscale modeling technique ought to focus on degrees of relative autonomy between scales, the measurable macroscale parameters of interest, indirect scaling relationships mediated by mesoscale features, and the degree of heterogeneity of the system’s mesoscale structures. The unique role that these (...) features play in multiscale modeling reveals several important methodological, epistemological, and metaphysical questions for future philosophical investigations into multiscale modeling. (shrink)

In Gandhi's Printing Press, Isabel Hofmeyr introduces readers to the nuances of the newspaper in a far-flung colony in the age when mail and news traveled by ship and when readers were encouraged by Gandhi to read slowly and deeply. This article explores the ways in which Thoreau's concept of slow reading influenced Gandhi and Hofmeyr herself. She discusses the community that surrounded Gandhi and the role it played in supporting the newspaper. Yet, I argue, the role of women of (...) all races as well as Coloured and black South African men in leading, modeling, and shaping the movement of resistance to pass laws and other racist legislation might have been integrated more into the main narrative. Gandhi's newspaper, Indian Opinion, reported on the pass law protests of the African women of Bloemfontein, and Abdurahman's APO newspaper (popular in the Coloured community) reported on Gandhi's protests. Indian Opinion included speeches given by John Dube, and it often praised Dube and the work at Ohlange and reprinted stories from the black press. I offer these remarks to supplement Hofmeyr's fascinating account by providing additional information in portraying the newspaper in its historical and social context. (shrink)

The paper evaluates the claims of Kwame Gyekye and Kwasi Wiredu that the Akan traditional governance structures are just as democratic or even more democratic that Western style representative democracies.

The paper traces the parallel paths and mutual influences of these three activists in South Africa. The paper points out that Gandhi often took steps in building his movement that echoed some of the same steps that Dube had done just before him. Also, Abdurahman, who had become Gandhi's friend in 1909, advocated for involving women in nonviolent action, and advocated the use of general strike, shortly before Gandhi incorporated both methods in his movement.

I ARGUE THAT SPINOZA’S DEVELOPMENT OF THE CONCEPT OF ’CONATION’ IS A CONSISTENT ANALYSIS BASED UPON HIS CLAIM THAT TELEOLOGICAL OR FUNCTIONAL EXPLANATION IS EITHER REDUCIBLE TO CAUSAL EXPLANATION (IN TERMS OF DRIVES) OR IS NOT GENUINELY EXPLANATORY. SEVERAL IMPORTANT CONSEQUENCES OF THIS FOR SPINOZA’S ACCOUNT OF HUMAN APPETITION ARE PURSUED, AND SOME CONSEQUENCES FOR HIS POLITICAL THEORY ARE MENTIONED IN CLOSING.